The MIF (8C2) Monoclonal Antibody from Bioss Inc. is a Rabbit Monoclonal antibody to Macrophage Migration Inhibitory Factor, and MIF. This antibody recognizes Human, Mouse, and Rat antigen. The MIF (8C2) Monoclonal Antibody has been validated for the following applications: Western Blot.
Description
Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity